Guess Which Immune Component cards

Guess Which Immune Component! game

Download our card game, which is all about the different cells and proteins found in the immune system

How to play

  • Play in pairs. You will try to guess which card the other player is holding.
  • Each of you should print out a set of cards, available in the downloadable resources section below. Cut them out and shuffle them.
  • Player one picks out a card from their set, and keeps it hidden from player two. Player two lays out their cards in front of them, face up. One of these cards will match the card that player one has picked.
  • Player two asks player one a series of questions to determine player one’s chosen card. After each question, player two turns face down any cards that they have eliminated through their questioning.
  • Keep a note of how many questions are asked in each round.
  • A guess counts as a question.
  • Once the card has been correctly identified, the players swap roles.
  • The winner is the person who determined their partner’s chosen card with the fewest questions.

Cards featured are: Basophil, Mast cell, Dendritic cell, Macrophage, Eosinophil, Neutrophil, Natural killer cell, Plasma B cell, Memory B cell, Memory T cell, Helper T cell, Cytotoxic T cell, Antibodies, Complement, Perforins, Antigens

For more on the immune system and to work out what questions you could ask, see our poster.

Suggested questions

Try these questions to get your game started – they’re not in any particular order.

Q: Does it occur in the non-specific (innate) immune system?

Answer is YES for: Basophil, Mast cell, Dendritic cell, Macrophage, Eosinophil, Neutrophil, Natural killer cell, Complement, Antigens

Q: Does it occur in the specific (adaptive) immune system?

Answer is YES for: Plasma B cell, Memory B cell, Memory T cell, Helper T cell, Cytotoxic T cell, Antibodies, Complement, Perforins, Antigens

Q: Does it have granules?

Answer is YES for: Basophil, Mast cell, Eosinophil, Neutrophil, Natural killer cell, Cytotoxic T cell

Q: Is it involved in inflammation?

Answer is YES for: Basophil, Mast cell, Neutrophil

Q: Is it a type of T cell?

Answer is YES for: Memory T cell, Helper T cell, Cytotoxic T cell

Q: Is it a type of B cell?

Answer is YES for: Plasma B cell, Memory B cell

Q: It is a type of cell?

Answer is YES for: Basophil, Mast cell, Dendritic cell, Macrophage, Eosinophil, Neutrophil, Natural killer cell, Plasma B cell, Memory B cell, Memory T cell, Helper T cell, Cytotoxic T cell

Q: Is it something other than a type of cell?

Answer is YES for: Complement, Antibodies, Perforins, Antigens

Q: Is it protein-based?

Answer is YES for: Complement, Antibodies, Perforins, Antigens

Q: Is it a leukocyte (or white blood cell)?

Answer is YES for: Basophil, Mast cell, Dendritic cell, Macrophage, Eosinophil, Neutrophil, Natural killer cell, Plasma B cell, Memory B cell, Memory T cell, Helper T cell, Cytotoxic T cell

Q: Is it a lymphocyte?

Answer is YES for: Natural killer cell, Plasma B cell, Memory B cell, Memory T cell, Helper T cell, Cytotoxic T cell

Q: Does it mature in the thymus?

Answer is YES for: Memory T cell, Helper T cell, Cytotoxic T cell, Natural killer cell

Q: Is it a phagocyte (something that engulfs infected or damaged cells)?

Answer is YES for: Dendritic cell, Macrophage, Eosinophil, Neutrophil

Q: Can it act as an antigen-presenting cell?

Answer is YES for: Dendritic cell, Macrophage

Q: Can it be presented by cells including macrophages and dendritic cells?

Answer is YES for: Antigens

Q: Can it release cytokines?

Answer is YES for: Natural killer cell, Helper T cell

Q: Does it undergo clonal selection?

Answer is YES for: Helper T cell, Cytotoxic T cell

Q: Is it part of a ‘foreign’ substance that can trigger an immune response?

Answer is YES for: Antigens

Lead image:

Bret Syfert, ‘Big Picture’ CC BY

Downloadable resources

About this resource

This resource was first published in ‘Immune System’ in January 2015.

Topic:
Immunology
Issue:
Immune System
Education levels:
16–19, Continuing professional development